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AI-powered tools generate real time insights into antibiotic resistance

  • Research Collaboration:
    • Conducted by IIIT-Delhi, CHRI-PATH, Tata 1mg, and Indian Council of Medical Research (ICMR).
    • Focus on developing AI-driven tools for antimicrobial resistance (AMR) surveillance.

Relevance : GS 2(Health ) , GS 3(Technology)

  • Key Tool Developed – AMRSense:
    • Utilizes routine hospital data (blood, sputum, urine cultures) for real-time AMR insights.
    • Provides global, national, and hospital-level AMR trends.
    • Cost-effective alternative to expensive genomic approaches.
  • Findings from Six-Year Study (Published in The Lancet Regional Health – Southeast Asia):
    • Analyzed data from 21 tertiary care centers under ICMR’s AMR surveillance network.
    • Identified directional relationships between antibiotic pairs and resistance patterns.
    • Rising resistance to one antibiotic can predict increased resistance to another over time.
  • Innovations in AMR Surveillance:
    • AMROrbit Scorecard:
      • Visualizes hospital/department resistance trends against global medians and rates.
      • Facilitates timely interventions by showing ideal resistance quadrants (low baseline, low rate of change).
      • Awarded at the 2024 AMR Surveillance Data Challenge.
  • AIs Role in Public Health and Clinical Settings:
    • Enhances antimicrobial stewardship through data-driven decisions.
    • Compares AMR rates across hospitals, cities, and departments.
    • Augments traditional surveillance systems with real-time data visualizations.
  • Challenges & Limitations:
    • AI models rely on consistent, digital surveillance data; limited in data-deficient regions.
    • Environmental factors (e.g., antibiotic use in poultry, soil contamination) also influence AMR but are not fully integrated yet.
  • Future Directions:
    • Plan to integrate hospital data with antibiotic sales and environmental data for comprehensive AMR analysis.
    • Aim to improve public health decision-making and policy formulation through expanded data integration.
  • Reliability of Models:
    • Models validated against historical data show accuracy in detecting AMR trends.
    • Global studies confirm the increasing rate of AMR captured by the AI models.

This development aligns with global health goals to combat antimicrobial resistance through timely data-driven interventions and improved public health strategies.


February 2025
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