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New Blood Test Measures Ageing Pace through DNA Methylation

Context:

Researchers have developed a groundbreaking blood test that measures the pace of ageing by studying DNA methylation. The test examines how an enzyme adds methyl groups to DNA in older adults, establishing a correlation between this biological process and ageing. This innovative approach offers a promising method to assess an individual’s biological age, providing valuable insights into the ageing process and potentially enabling personalized interventions to promote healthy ageing and prevent age-related diseases.

Relevance:

Facts for Prelims

Geroscience: An Overview

Definition

  • Geroscience is an interdisciplinary field dedicated to understanding the biological mechanisms of aging and age-related diseases.
Key Areas of Study
  • Biological Factors
    • DNA Methylation: A process where methyl groups (CH3) are added to the DNA molecule, crucial for regulating gene expression and maintaining genome stability.
    • Enzyme Activity: Including gerozyme, an aging-associated enzyme.
  • External Factors
    • Socio-economic influences.
    • Lifestyle interventions such as:
      • Nutrition
      • Exercise
      • Music therapy
Objective
  • To develop strategies, including drug interventions targeting specific aging-related processes, to promote healthy aging and combat age-related conditions like dementia.

-Source: The Hindu


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